Acute and chronic effects of lithium on BDNF and GDNF mRNA and protein levels in rat primary neuronal, astroglial and neuroastroglia cultures

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Emamghoreishi, Masoumeh; Keshavarz, Mojtaba; Nekooeian, Ali Akbar;
  • Publisher: Mashhad University of Medical Sciences
  • Journal: Iranian Journal of Basic Medical Sciences, volume 18, issue 3, pages 240-246 (issn: 2008-3866, eissn: 2008-3874)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC4414989
  • Subject: Original Article | Lithium | BDNF | Neuro-astroglial | GDNF | Culture | Astrocytes | Neurons
    mesheuropmc: nervous system

Objective(s): The neuroprotective effect of lithium has been attributed to its therapeutic action. However, the role of glial cells particularly astrocytes, and the possible interactions between neurons and astrocytes in neuroprotective effects of lithium have been disr... View more
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