publication . Other literature type . 1993

The Limited Ability Of Inferior Petrosal Sinus Sampling With Corticotropin-Releasing Hormone To Distinguish Cushing Disease From Pseudo-Cushing States or Normal Physiology

Yanovski, Jack A.; Cutler, Gordon B.; Doppman, John L.; Miller, Donald L.; Chrousos, George P.; Oldfield, Edward H.; Nieman, Lynnette K.;
Open Access English
  • Published: 01 Aug 1993
Abstract
To determine whether or not petrosal sinus sampling is useful to distinguish patients with mild or intermittent Cushing disease from normal subjects and from individuals with pseudo-Cushing states, we performed bilateral inferior petrosal sinus sampling for adrenocorticotropin (ACTH) before and after the administration of corticotropin-releasing hormone (CRH) in 7 eucortisolemic volunteers, 8 hypercortisolemic patients with pseudo-Cushing states, and 40 patients with ACTH-dependent Cushing disease whose urine free cortisol excretion was within the range found in patients having pseudo-Cushing states (<1000nmol/d [<360 μg/d]). The ACTH level, the ratio of the inf...
Subjects
mesheuropmc: endocrine systemhormones, hormone substitutes, and hormone antagonists
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Other literature type . 1993
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