DEIsoM: a hierarchical Bayesian model for identifying differentially expressed isoforms using biological replicates

Article English OPEN
Peng, Hao ; Yang, Yifan ; Zhe, Shandian ; Wang, Jian ; Gribskov, Michael ; Qi, Yuan (2017)
  • Publisher: Oxford University Press
  • Journal: Bioinformatics, volume 33, issue 19, pages 3,018-3,027 (issn: 1367-4803, eissn: 1367-4811)
  • Related identifiers: pmc: PMC5870796, doi: 10.1093/bioinformatics/btx357
  • Subject: Sequence Analysis | Original Papers

Abstract Motivation High-throughput mRNA sequencing (RNA-Seq) is a powerful tool for quantifying gene expression. Identification of transcript isoforms that are differentially expressed in different conditions, such as in patients and healthy subjects, can provide insig... View more
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