publication . Other literature type . Article . 2011

Transcriptome of Proteus mirabilis in the Murine Urinary Tract: Virulence and Nitrogen Assimilation Gene Expression

Melanie M. Pearson; Alejandra Yep; Sara N. Smith; Harry L. T. Mobley;
  • Published: 01 Jul 2011
  • Publisher: American Society for Microbiology
Abstract
<jats:title>ABSTRACT</jats:title><jats:p>The enteric bacterium<jats:named-content xmlns:xlink="http://www.w3.org/1999/xlink" content-type="genus-species" xlink:type="simple">Proteus mirabilis</jats:named-content>is a common cause of complicated urinary tract infections. In this study, microarrays were used to analyze<jats:named-content xmlns:xlink="http://www.w3.org/1999/xlink" content-type="genus-species" xlink:type="simple">P. mirabilis</jats:named-content>gene expression<jats:italic>in vivo</jats:italic>from experimentally infected mice. Urine was collected at 1, 3, and 7 days postinfection, and RNA was isolated from bacteria in the urine for transcriptional ...
Subjects
free text keywords: Molecular Genomics, Immunology, Microbiology, Parasitology, Infectious Diseases, In vivo, Molecular biology, Glutamine synthetase, Escherichia coli, medicine.disease_cause, medicine, Proteus mirabilis, biology.organism_classification, biology, Nitrogen assimilation, Gene expression, Glutamate dehydrogenase, Enterobacteriaceae
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