Patterns of brain atrophy associated with episodic memory and semantic fluency decline in aging

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Pelletier, Amandine; Bernard, Charlotte; Dilharreguy, Bixente; Helmer, Catherine; Le Goff, Melanie; Chanraud, Sandra; Dartigues, Jean-François; Allard, Michèle; Amieva, Hélène; Catheline, Gwénaëlle;
  • Publisher: Impact Journals LLC
  • Journal: Aging (Albany NY),volume 9,issue 3,pages741-752 (eissn: 1945-4589)
  • Related identifiers: pmc: PMC5391228, doi: 10.18632/aging.101186
  • Subject: semantic fluency decline | episodic memory decline | Research Paper | grey matter atrophy

The cerebral substratum of age-related cognitive decline was evaluated in an elderly-cohort followed for 12 years (n=306). Participants, free of dementia, received neuropsychological assessments every two years and an MRI exam at baseline and four years later. Cognitive... View more
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