DNA-segment-facilitated dissociation of Fis and NHP6A from DNA detected via single-molecule mechanical response

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Giuntoli, Rebecca D.; Linzer, Nora B.; Banigan, Edward J.; Sing, Charles E.; de la Cruz, Monica Olvera; Graham, John S.; Johnson, Reid C.; Marko, John F.;

The rate of dissociation of a DNA-protein complex is often considered to be a property of that complex, without dependence on other nearby molecules in solution. We study the kinetics of dissociation of the abundant E. coli nucleoid protein Fis from DNA, using a single-... View more
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