Biochemical characterization of variants of canine CYP1A1 using heterologous expression

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YU, Hee Jeong; LEE, Seung Heon; LEE, Seungwoo; CHOI, Yu Jung; OH, Dayoung; NAM, Ki-Hoan; YUN, YoungMin; RYU, Doug-Young;

Cytochrome P450 1A1 (CYP1A1) is a heme-containing mono-oxygenase involved in metabolism of environmental contaminants. Two variants of dog CYP1A1 with a single residue difference were identified and designated Sap1 and Sap2. Compared with Sap1, Sap2 had a Trp50Leu subst... View more
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