publication . Article . 2019

A systematic review of the long-term efficacy of low-intensity shockwave therapy for vasculogenic erectile dysfunction

Brunckhorst, Oliver; Wells, Lauren; Teeling, Fiona; Muir, Gordon; Muneer, Asif; Ahmed, Kamran;
Open Access
  • Published: 01 May 2019 Journal: International Urology and Nephrology, volume 51, pages 773-781 (issn: 0301-1623, eissn: 1573-2584, Copyright policy)
  • Publisher: Springer Science and Business Media LLC
  • Country: United Kingdom
Abstract
Purpose To look at the evidence base for LISWT as a treatment modality for vasculogenic erectile dysfunction, focusing on the long-term outcomes at over 6 months following treatment. Methods A systematic literature search was conducted utilising MEDLINE and Scopus databases from 2010 to September 2018 by two independent reviewers. Outcome measures extracted for long-term efficacy included International Index of Erectile Function scores and Erection Hardness Scores. Subgroup analysis for LISWT effectiveness included age, PDE5i responsiveness, presence of vascular co-morbidities and smoking status. Results The search identified eleven studies, representing a total...
Subjects
free text keywords: /dk/atira/pure/subjectarea/asjc/2700/2727, /dk/atira/pure/subjectarea/asjc/2700/2748, Urology, Nephrology, medicine.medical_specialty, medicine, Vasculogenic erectile dysfunction, Vasculogenic Impotence, Erectile dysfunction, medicine.disease, business.industry, business, Extracorporeal shockwave therapy, medicine.medical_treatment, Internal medicine, Diabetes mellitus, Urology - Review
24 references, page 1 of 2

Wyllie, MG. The underlying pathophysiology and causes of erectile dysfunction. Clin Cornerstone. 2005; 7: 19-27 [PubMed] [DOI]

Vardi, Y, Appel, B, Jacob, G. Can low-intensity extracorporeal shockwave therapy improve erectile function? A 6-month follow-up pilot study in patients with organic erectile dysfunction. Eur Urol. 2010; 58: 243-248 [OpenAIRE] [PubMed] [DOI]

Hatzimouratidis, K, Salonia, A, Adaikan, G. Pharmacotherapy for erectile dysfunction: Recommendations from the Fourth International Consultation for Sexual Medicine (ICSM 2015). J Sex Med. 2016; 13: 465-488 [OpenAIRE] [PubMed] [DOI]

4.NHS England (2016) Clinical Commissioning Policy: Penile Prosthesis surgery for end stage erectile dysfunction. NHS England. https://www.england.nhs.uk/wp-content/uploads/2018/07/Penile-prostheses-for-end-stage-erectile-dysfunction.pdf. Accessed 28 November 2018

Hatzimouratidis, K, Giuliano, F, Moncada, I. EAU guidelines: male sexual dysfunction. 2018

Wang, HJ, Cheng, JH, Chuang, YC. Potential applications of low-energy shock waves in functional urology. Int J Urol. 2017; 24: 573-581 [OpenAIRE] [PubMed] [DOI]

Nishida, T, Shimokawa, H, Oi, K. Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo. Circulation. 2004; 110: 3055-3061 [PubMed] [DOI]

Aicher, A, Heeschen, C, Sasaki, K. Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia. Circulation. 2006; 114: 2823-2830 [OpenAIRE] [PubMed] [DOI]

Hausner, T, Pajer, K, Halat, G. Improved rate of peripheral nerve regeneration induced by extracorporeal shock wave treatment in the rat. Exp Neurol. 2012; 236: 363-370 [OpenAIRE] [PubMed] [DOI]

Moher, D, Liberati, A, Tetzlaff, J. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med. 2009; 151: 264-269 [OpenAIRE] [PubMed] [DOI]

Higgins, JP, Altman, DG, Gøtzsche, PC. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ. 2011; 343: d5928 [OpenAIRE] [PubMed] [DOI]

Guyatt, G, Oxman, AD, Akl, EA. GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables. J Clin Epidemiol. 2011; 64: 383-394 [OpenAIRE] [PubMed] [DOI]

Kitrey, ND, Vardi, Y, Appel, B. Low intensity shock wave treatment for erectile dysfunction-how long does the effect last?. J Urol. 2018; 200: 167-170 [OpenAIRE] [PubMed] [DOI]

Kalyvianakis, D, Memmos, E, Mykoniatis, I. Low-intensity shockwave therapy for erectile dysfunction: a randomized clinical trial comparing 2 treatment protocols and the impact of repeating treatment. J Sex Med. 2018; 15: 334-345 [OpenAIRE] [PubMed] [DOI]

Kalyvianakis, D, Hatzichristou, D. Low-intensity shockwave therapy improves hemodynamic parameters in patients with vasculogenic erectile dysfunction: a triplex ultrasonography-based sham-controlled trial. J Sex Med. 2017; 14: 891-897 [OpenAIRE] [PubMed] [DOI]

24 references, page 1 of 2
Abstract
Purpose To look at the evidence base for LISWT as a treatment modality for vasculogenic erectile dysfunction, focusing on the long-term outcomes at over 6 months following treatment. Methods A systematic literature search was conducted utilising MEDLINE and Scopus databases from 2010 to September 2018 by two independent reviewers. Outcome measures extracted for long-term efficacy included International Index of Erectile Function scores and Erection Hardness Scores. Subgroup analysis for LISWT effectiveness included age, PDE5i responsiveness, presence of vascular co-morbidities and smoking status. Results The search identified eleven studies, representing a total...
Subjects
free text keywords: /dk/atira/pure/subjectarea/asjc/2700/2727, /dk/atira/pure/subjectarea/asjc/2700/2748, Urology, Nephrology, medicine.medical_specialty, medicine, Vasculogenic erectile dysfunction, Vasculogenic Impotence, Erectile dysfunction, medicine.disease, business.industry, business, Extracorporeal shockwave therapy, medicine.medical_treatment, Internal medicine, Diabetes mellitus, Urology - Review
24 references, page 1 of 2

Wyllie, MG. The underlying pathophysiology and causes of erectile dysfunction. Clin Cornerstone. 2005; 7: 19-27 [PubMed] [DOI]

Vardi, Y, Appel, B, Jacob, G. Can low-intensity extracorporeal shockwave therapy improve erectile function? A 6-month follow-up pilot study in patients with organic erectile dysfunction. Eur Urol. 2010; 58: 243-248 [OpenAIRE] [PubMed] [DOI]

Hatzimouratidis, K, Salonia, A, Adaikan, G. Pharmacotherapy for erectile dysfunction: Recommendations from the Fourth International Consultation for Sexual Medicine (ICSM 2015). J Sex Med. 2016; 13: 465-488 [OpenAIRE] [PubMed] [DOI]

4.NHS England (2016) Clinical Commissioning Policy: Penile Prosthesis surgery for end stage erectile dysfunction. NHS England. https://www.england.nhs.uk/wp-content/uploads/2018/07/Penile-prostheses-for-end-stage-erectile-dysfunction.pdf. Accessed 28 November 2018

Hatzimouratidis, K, Giuliano, F, Moncada, I. EAU guidelines: male sexual dysfunction. 2018

Wang, HJ, Cheng, JH, Chuang, YC. Potential applications of low-energy shock waves in functional urology. Int J Urol. 2017; 24: 573-581 [OpenAIRE] [PubMed] [DOI]

Nishida, T, Shimokawa, H, Oi, K. Extracorporeal cardiac shock wave therapy markedly ameliorates ischemia-induced myocardial dysfunction in pigs in vivo. Circulation. 2004; 110: 3055-3061 [PubMed] [DOI]

Aicher, A, Heeschen, C, Sasaki, K. Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia. Circulation. 2006; 114: 2823-2830 [OpenAIRE] [PubMed] [DOI]

Hausner, T, Pajer, K, Halat, G. Improved rate of peripheral nerve regeneration induced by extracorporeal shock wave treatment in the rat. Exp Neurol. 2012; 236: 363-370 [OpenAIRE] [PubMed] [DOI]

Moher, D, Liberati, A, Tetzlaff, J. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med. 2009; 151: 264-269 [OpenAIRE] [PubMed] [DOI]

Higgins, JP, Altman, DG, Gøtzsche, PC. The Cochrane Collaboration’s tool for assessing risk of bias in randomised trials. BMJ. 2011; 343: d5928 [OpenAIRE] [PubMed] [DOI]

Guyatt, G, Oxman, AD, Akl, EA. GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables. J Clin Epidemiol. 2011; 64: 383-394 [OpenAIRE] [PubMed] [DOI]

Kitrey, ND, Vardi, Y, Appel, B. Low intensity shock wave treatment for erectile dysfunction-how long does the effect last?. J Urol. 2018; 200: 167-170 [OpenAIRE] [PubMed] [DOI]

Kalyvianakis, D, Memmos, E, Mykoniatis, I. Low-intensity shockwave therapy for erectile dysfunction: a randomized clinical trial comparing 2 treatment protocols and the impact of repeating treatment. J Sex Med. 2018; 15: 334-345 [OpenAIRE] [PubMed] [DOI]

Kalyvianakis, D, Hatzichristou, D. Low-intensity shockwave therapy improves hemodynamic parameters in patients with vasculogenic erectile dysfunction: a triplex ultrasonography-based sham-controlled trial. J Sex Med. 2017; 14: 891-897 [OpenAIRE] [PubMed] [DOI]

24 references, page 1 of 2
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publication . Article . 2019

A systematic review of the long-term efficacy of low-intensity shockwave therapy for vasculogenic erectile dysfunction

Brunckhorst, Oliver; Wells, Lauren; Teeling, Fiona; Muir, Gordon; Muneer, Asif; Ahmed, Kamran;