publication . Doctoral thesis . 2014

The role of Six1 in muscle progenitor cells and the establishment of fast-twitch muscle fibres

Nord, Hanna;
Open Access English
  • Published: 01 Jan 2014
  • Publisher: Umeå universitet, Umeå centrum för molekylär medicin (UCMM)
  • Country: Sweden
Myogenesis is the process of skeletal muscle tissue formation where committed muscle progenitor cells differentiate into skeletal muscle fibres. Depending on the instructive cues the muscle progenitor cells receive they will differentiate into specific fibre types with different properties. The skeletal muscle fibres can be broadly classified as fast-twitch fibres or slow-twitch fibres, based on their contractile speed. However, subgroups of fast- and slow-twitch fibres with different metabolic properties, endurance and different isoforms of sarcomeric components have also been identified, adding complexity to the process of muscle tissue patterning. The skeleta...
free text keywords: Myogenesis, zebrafish, muscle fibre, patterning, fmyhc, myl1, Six1, Pax7, Basic Medicine, Medicinska och farmaceutiska grundvetenskaper
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