publication . Article . 2011

Hemodynamic aspects of mitral regurgitation assessed by generalized phase-contrast MRI

Petter Dyverfeldt; John-Peder Escobar Kvitting; Carl-Johan Carlhäll; Gabriella Boano; Andreas Sigfridsson; Ulf Hermansson; Ann F. Bolger; Jan Engvall; Tino Ebbers;
Open Access
  • Published: 01 Jan 2011 Journal: Journal of Magnetic Resonance Imaging, volume 33, pages 582-588 (issn: 1053-1807, Copyright policy)
  • Publisher: Wiley
  • Country: Sweden
Purpose: Mitral regurgitation creates a high velocity jet into the left atrium (LA), contributing both volume andpressure; we hypothesized that the severity of regurgitation would be reflected in the degree of LA flowdistortion. Material and Methods: Three-dimensional cine PC-MRI was applied to determine LA flow patterns andturbulent kinetic energy (TKE) in seven subjects (five patients with posterior mitral leaflet prolapse, two normalsubjects). In addition, the regurgitant volume and the time-velocity profiles in the pulmonary veins weremeasured. Results: The LA flow in the mitral regurgitation patients was highly disturbed with elevated values of TKE.Peak TKE...
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Medical Subject Headings: cardiovascular system
free text keywords: Radiology Nuclear Medicine and imaging, mitral valve insufficiency, turbulent flow, phase-contrast magnetic resonance imaging, pulmonary veins, blood flow velocity, Medical and Health Sciences, Medicin och hälsovetenskap, Medicine, business.industry, business, Mitral regurgitation, Radiology, medicine.medical_specialty, Cardiology, Phase contrast microscopy, law.invention, law, Hemodynamics, Left atrium, medicine.anatomical_structure, Internal medicine
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