publication . Article . 2011

Hemodynamic aspects of mitral regurgitation assessed by generalized phase-contrast MRI.

Dyverfeldt, Petter; Escobar Kvitting, John-Peder; Carlhäll, Carl Johan; Boano, Gabriella; Sigfridsson, Andreas; Hermansson, Ulf; Bolger, Ann F.; Engvall, Jan; Ebbers, Tino;
Open Access
  • Published: 24 Feb 2011 Journal: Journal of Magnetic Resonance Imaging, volume 33, pages 582-588 (issn: 1053-1807, Copyright policy)
  • Publisher: Wiley
  • Country: Sweden
Abstract
Purpose: Mitral regurgitation creates a high velocity jet into the left atrium (LA), contributing both volume andpressure; we hypothesized that the severity of regurgitation would be reflected in the degree of LA flowdistortion. Material and Methods: Three-dimensional cine PC-MRI was applied to determine LA flow patterns andturbulent kinetic energy (TKE) in seven subjects (five patients with posterior mitral leaflet prolapse, two normalsubjects). In addition, the regurgitant volume and the time-velocity profiles in the pulmonary veins weremeasured. Results: The LA flow in the mitral regurgitation patients was highly disturbed with elevated values of TKE.Peak TKE...
Subjects
Medical Subject Headings: cardiovascular system
free text keywords: mitral valve insufficiency, turbulent flow, phase-contrast magnetic resonance imaging, pulmonary veins, blood flow velocity, Medical and Health Sciences, Medicin och hälsovetenskap, Radiology Nuclear Medicine and imaging, Radiology, medicine.medical_specialty, medicine, Cardiology, Left atrium, medicine.anatomical_structure, Internal medicine, business.industry, business, Hemodynamics, Phase contrast microscopy, law.invention, law, Mitral regurgitation
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