publication . Doctoral thesis . 2013

Phenotypic and chemotypic characterization of GABA-shunt mutants in Arabidopsis thaliana

Mekonnen, Dereje Worku;
Open Access English
  • Published: 15 Aug 2013
  • Publisher: Plant Physiology
  • Country: Germany
Abstract
Gamma-Aminobutyric acid (GABA) is a four carbon non protein amino acid, and the pathway that involves its production and degradation is called the GABA shunt. The GABA shunt is a short enzymatic pathway that involves three enzymes: glutamate decarboxylase (GAD), GABA transaminase (GABA-T) and succinic semi aldehyde dehydrogenase (SSADH). GABA shunt is conserved almost in all organisms studied so far. The pathway starts in the cytosol and finishes in mitochondria in higher organisms like plants and mammals, whereas, in yeast it is exclusively cytosolic. The presence of GABA in plants has been known since over half a century ago. The induction of its accumulation ...
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Subjects
Medical Subject Headings: nervous system
free text keywords: ddc:570
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Doctoral thesis . 2013
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Nationality: Ethiopian, Address: Deutzer Ring 5, 50679 Cologne, Germany Cell Phone: +4917670278300, e-mail: dmekonne@smail.uni-koeln.de April 21-22, 2010

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