publication . Article . 2004

Ternary iron(ii) complex with an emissive imidazopyridine arm from Schiff base cyclizations and its oxidative DNA cleavage activity

Arindam Mukherjee; Shanta Dhar; Munirathinam Nethaji; Akhil R. Chakravarty;
Open Access
  • Published: 06 Dec 2004
  • Publisher: Royal Society of Chemistry (RSC)
  • Country: India
Abstract
The ternary iron(II) complex [Fe(L')(L")] $(PF_6)_3(1)$ as a synthetic model for the bleomycins, where L' and L" are formed from metal-mediated cyclizations of N,N -(2-hydroxypropane-1,3-diyl)bis(pyridine-2-aldimine)(L), is synthesized and structurally characterized by X-ray crystallography. In the six-coordinate iron(II) complex, ligands L' and L" show tetradentate and bidentate chelating modes of bonding. Ligand L' is formed from an intramolecular attack of the alcoholic OH group of L to one imine moiety leading to the formation of a stereochemically constrained five-membered ring. Ligand L" which is formed from an intermolecular reaction involving one imine m...
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Subjects
free text keywords: Inorganic Chemistry, Inorganic & Physical Chemistry, Imidazopyridine, Hydroxyl radical, chemistry.chemical_compound, chemistry, Moiety, Schiff base, Stereochemistry, Denticity, Imine, Ligand, Intramolecular force, Polymer chemistry
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