publication . Article . Other literature type . 2014

Factors that predict thrombosis in relatives of patients with venous thromboembolism.

Couturaud, Francis; Leroyer, Christophe; Tromeur, Cecile; Julian, Jim A.; Kahn, Susan R.; Ginsberg, Jeffrey S.; Wells, Philip S.; Douketis, James D.; Mottier, Dominique; Kearon, Clive;
Open Access English
  • Published: 25 Sep 2014
  • Publisher: HAL CCSD
  • Country: France
Abstract
International audience; When counseling first-degree relatives of patients with venous thromboembolism (VTE), it is important to know whether factors other than thrombophilia influence their risk for thrombosis. We assessed the risk for VTE in 915 first-degree relatives of patients with provoked VTE, compared this with the risk in 1752 first-degree relatives of patients with unprovoked VTE, and then combined data from the 2 groups of relatives to identify predictors of thrombosis. There had been 123 VTEs in 2617 first-degree relatives (0.12 per 100 person-years). The risk for VTE in first-degree relatives was higher if the index cases had an unprovoked compared ...
Subjects
Medical Subject Headings: cardiovascular diseasesequipment and supplies
free text keywords: Venous thromboembolism, Relatives of patients, Factors that predict thrombosis, [SDV]Life Sciences [q-bio], [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, [ SDV ] Life Sciences [q-bio], [ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathology, [ SDV.MHEP.CSC ] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Thrombosis and Hemostasis, Immunology, Cell Biology, Biochemistry, Hematology, Thrombosis, medicine.disease, medicine, Pediatrics, medicine.medical_specialty, Factor V Leiden, Thrombophilia, business.industry, business, Odds ratio, Confidence interval, Cross-sectional study, Factor V, biology.protein, biology, Index case
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