publication . Thesis . 2013

Electrospun three dimensional scaffolds for bone tissue regeneration

Paşcu, Elena Irina;
Open Access English
  • Published: 01 Nov 2013
  • Country: Ireland
Abstract
Bone is a complex and highly specialized form of connective tissue which acts as the main supporting organ of the body. It is hard and dynamic by its nature, with a unique combination of organic and inorganic elements embedded in a fibrous extracellular matrix (ECM), onto which cells attach, proliferate and differentiate. When bone repair mechanisms fail, due to infection or defect magnitude, bone formation can be stimulated with the use of autologous bone grafts or donor allografts. However, autografts are associated with limitations such as donor site morbidity and limited availability, while allografts have the potential to cause an immune response and also c...
Subjects
free text keywords: Materials, Biotechnology, Mechanical engineering, Cell biology, Biomedical engineering
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