publication . Thesis . 2002

The development and applications of polyclonal and monoclonal antibodies for the detection of illicit drugs in saliva samples

Fanning, Lorna M.;
Open Access English
  • Published: 01 Jan 2002
  • Country: Ireland
Abstract
Anti-tetrahydrocannabinol (THC), anti-cocaine and anti-morphine polyclonal antibodies were produced. These antibodies were successfully applied to an ELISA format for the detection of THC, cocaine, and morphine in saliva samples. Monoclonal antibodies against amphetamine and its derivatives were produced using two different conjugates, amphetamine-bovine serum albumin and methamphetaminebovine serum albumin. Two successful clones were produced, and the antibodies were applied to an ELISA format for the detection of amphetamine, methamphetamine, and the other common amphetamine derivatives, such as methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine...
Subjects
Medical Subject Headings: mental disorders
free text keywords: Biotechnology, Biosensors
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