Triazolophostins: a library of novel and potent agonists of IP3 receptors

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Vibhute, Amol M; Konieczny, Vera; Taylor, Colin; Sureshan, Kana M;
  • Publisher: Organic and Biomolecular Chemistry

IP3 receptors are channels that mediate the release of Ca2+ from the intracellular stores of cells stimulated by hormones or neurotransmitters. Adenophostin A (AdA) is the most potent agonist of IP3 receptors, with the β-anomeric adenine contributing to the increased po... View more
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