Advancing haematopoietic stem and progenitor cell biology through single-cell profiling

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Hamey, Fiona; Nestorowa, Sonia; Wilson, Nicola; Göttgens, Berthold;
(2016)
  • Publisher: FEBS Letters
  • Related identifiers: doi: 10.17863/CAM.471
  • Subject: computational models | fate choice | haematopoietic stem/progenitor cells | heterogeneity | lineage differentiation | single-cell

Haematopoietic stem and progenitor cells (HSPCs) sit at the top of the haematopoietic hierarchy, and their fate choices need to be carefully controlled to ensure balanced production of all mature blood cell types. As cell fate decisions are made at the level of the indi... View more
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