publication . Article . Review . 2011

Scheduled feeding results in adipogenesis and increased acylated ghrelin

Verbaeys, I.; Tolle, V.; SWENNEN, Quirine; Zizzari, P.; Buyse, J.; Epelbaum, J.; Cokelaere, M.;
Open Access
  • Published: 01 Jan 2011 Journal: American Journal of Physiology-Endocrinology and Metabolism, volume 300, pages E1103-E1111 (issn: 0193-1849, eissn: 1522-1555, Copyright policy)
  • Publisher: American Physiological Society
  • Country: Belgium
Abstract
Ghrelin, known to stimulate adipogenesis, displays an endogenous secretory rhythmicity closely related to meal patterns. Therefore, a chronic imposed feeding schedule might induce modified ghrelin levels and consequently adiposity. Growing Wistar rats were schedule-fed by imposing a particular fixed feeding schedule of 3 meals/day without caloric restriction compared with total daily control intake. After 14 days, their body composition was measured by DEXA and compared with ad libitum-fed controls and to rats daily intraperitoneal injection with ghrelin. Feeding patterns, circadian activity, and pulsatile acylated ghrelin variations were monitored. After 14 day...
Subjects
Medical Subject Headings: digestive, oral, and skin physiology
free text keywords: Physiology (medical), Physiology, Endocrinology, Diabetes and Metabolism, Calorie restriction, Obesity, medicine.disease, medicine, Circadian rhythm, Ghrelin, Intermittent fasting, Adipose tissue, Meal, Endocrinology, medicine.medical_specialty, Biology, Internal medicine, Adipogenesis, metabolism; obesity; feeding patterns; meal frequency; dual-energy X-ray absorptiometry
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publication . Article . Review . 2011

Scheduled feeding results in adipogenesis and increased acylated ghrelin

Verbaeys, I.; Tolle, V.; SWENNEN, Quirine; Zizzari, P.; Buyse, J.; Epelbaum, J.; Cokelaere, M.;