publication . Article . Review . 2016

Postoperative radiotherapy for lung cancer: Is it worth the controversy?

Billiet, Charlotte; Peeters, Stephanie; Decaluwe, Herbert; Vansteenkiste, Johan; Mebis, Jeroen; De Ruysscher, Dirk;
Open Access English
  • Published: 01 Dec 2016
  • Publisher: OXFORD
Abstract
Introduction: The role of postoperative radiation therapy (PORT) in patients with completely resected non-small cell lung cancer (NSCLC) with pathologically involved mediastinal lymph nodes (N2) remains unclear. Despite a reduction of local recurrence (LR), its effect on overall survival (OS) remains unproven. Therefore we conducted a review of the current literature. Methods: To investigate the benefit and safety of modern PORT, we identified published phase III trials for PORT. We investigated modern PORT in low-risk (ypN0/1 and RO) and high-risk (ypN2 and/or R1/2) patients with stage III-N2 NSCLC treated with induction chemotherapy and resection. Results: Sev...
Subjects
free text keywords: Post-operative radiotherapy; Non-small-cell lung cancer; Review, Post-operative radiotherapy, Review, Non-small-cell lung cancer
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publication . Article . Review . 2016

Postoperative radiotherapy for lung cancer: Is it worth the controversy?

Billiet, Charlotte; Peeters, Stephanie; Decaluwe, Herbert; Vansteenkiste, Johan; Mebis, Jeroen; De Ruysscher, Dirk;