Isoelectrofocusing and PCR Amplification-Reverse Hybridization Assay in Evaluation of Alpha-1-Antitrypsin Deficiency

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Beletić, Anđelo; Đorđević, Valentina; Dudvarski-Ilić, Aleksandra; Obradović, Ivana; Mirković, Duško; Ilić, Mirka; Radojković, Dragica; Majkić-Singh, Nada;
(2009)
  • Publisher: Društvo medicinskih biohemičara Srbije, Beograd i Versita
  • Identifiers: doi: 10.2478/v10011-009-0023-x
  • Subject: isoelectrofocusing | PCR-reverse hybridization | alpha-1-antitrypsin

Alpha-1-antitrypsin deficiency is a potentially lethal genetic disorder, which has pulmonary and liver manifestations. The standardized biochemical and molecular diagnostic protocol for detection of clinically relevant alleles is needed. The paper summarizes current con... View more
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