Genome-wide CpG island methylation analysis implicates novel genes in the pathogenesis of renal cell carcinoma.

Article, Other literature type OPEN
Ricketts, Christopher J.; Morris, Mark R.; Gentle, Dean; Brown, Michael; Wake, Naomi; Woodward, Emma R.; Clarke, Noel; Latif, Farida; Maher, Eamonn R.;
  • Publisher: Landes Bioscience
  • Related identifiers: pmc: PMC3335951, doi: 10.4161/epi.7.3.19103
  • Subject: Molecular Biology | RCC | Methylation | Renal cell carcinoma (RCC) | /dk/atira/pure/subjectarea/asjc/1300/1312 | Renal Cancer | /dk/atira/pure/subjectarea/asjc/1300/1306 | Research Paper | Epigenetics | Cancer Research
    mesheuropmc: urologic and male genital diseases

In order to identify novel candidate tumor suppressor genes (TSGs) implicated in renal cell carcinoma (RCC), we performed genome-wide methylation profiling of RCC using the HumanMethylation27 BeadChips to assess methylation at >14,000 genes. Two hundred and twenty hy... View more
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