Immunohistochemical analysis of Sonic hedgehog signalling in normal human urinary tract development

Article, Other literature type OPEN
Jenkins, D.; Winyard, P. J. D.; Woolf, A. S.;
(2007)
  • Publisher: BLACKWELL PUBLISHING
  • Related identifiers: doi: 10.1111/j.1469-7580.2007.00808.x, pmc: PMC2375778
  • Subject: Uroplakin | Anatomy | Smooth muscle | /dk/atira/pure/subjectarea/asjc/1100/1101 | Urothelium | Collecting duct | bladder, collecting duct, smooth muscle, urothelium, uroplakin, BONE MORPHOGENETIC PROTEIN-4, DIFFERENTIATION, PATHWAY, MOUSE, EXPRESSION, MUTATIONS, KIDNEY, GENES, MALFORMATIONS, DEFECTS | Bladder | Original Articles | Agricultural and Biological Sciences (miscellaneous) | /dk/atira/pure/subjectarea/asjc/2700/2702
    mesheuropmc: animal structures | embryonic structures

Studies of mouse mutants have demonstrated that Sonic hedgehog (SHH) signalling has a functional role in morphogenesis and differentiation at multiple sites within the forming urinary tract, and urinary tract malformations have been reported in humans with mutations tha... View more
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