publication . Article . 1993

Epidemiology of bovine trypanosomiasis in the Ghibe valley, southwest Ethiopia. 3. Occurrence of populations of Trypanosoma congolense resistant to diminazene, isometamidium and homidium

Codjia, V.; Woudyalew Mulatu,; Majiwa, P.A.O.; Leak, S.G.A.; Rowlands, G.J.; Authié, Edith; D'Ieteren, G.D.M.; Peregrine, A.S.;
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  • Published: 01 Jan 1993 Journal: Acta Tropica, volume 53, pages 151-163 (issn: 0001-706X, Copyright policy)
  • Publisher: Elsevier BV
  • Country: France
Abstract
Abstract In July 1989, blood samples were collected from parasitaemic cattle in the Ghibe valley, Ethiopia, frozen in liquid nitrogen and transported to Nairobi, Kenya. Twelve of the stabilates were inoculated into individual Boran (Bos indicus) calves and characterised for their sensitivity, in turn, to diminazene aceturate (Berenil®), isometamidium chloride (Samorin®) and homidium chloride (Novidium®). All 12 stabilates produced infections which were shown to be Trypanosoma congolense and resistant to treatment with diminazene aceturate at a dose of 7.0 mg kg−1 body weight (b.w.). Eleven of the infections were also resistant to isometamidium chloride at a dose...
Subjects
free text keywords: Parasitology, Infectious Diseases, General Medicine, Virology, Trypanosoma, biology.organism_classification, biology, Drug resistance, Inoculation, Isometamidium chloride, chemistry.chemical_compound, chemistry, Immunology, Diminazene, medicine.drug, medicine, Veterinary medicine, Trypanosomiasis, medicine.disease, Pesticide resistance, Homidium Chloride, L72 - Organismes nuisibles des animaux, Bovin, Trypanosoma congolense, Épidémiologie, Résistance aux produits chimiques, http://aims.fao.org/aos/agrovoc/c_1391, http://aims.fao.org/aos/agrovoc/c_27401, http://aims.fao.org/aos/agrovoc/c_2615, http://aims.fao.org/aos/agrovoc/c_5736, http://aims.fao.org/aos/agrovoc/c_2676
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publication . Article . 1993

Epidemiology of bovine trypanosomiasis in the Ghibe valley, southwest Ethiopia. 3. Occurrence of populations of Trypanosoma congolense resistant to diminazene, isometamidium and homidium

Codjia, V.; Woudyalew Mulatu,; Majiwa, P.A.O.; Leak, S.G.A.; Rowlands, G.J.; Authié, Edith; D'Ieteren, G.D.M.; Peregrine, A.S.;