publication . Conference object . 2005

Development of colonic 5-ASA beads

Iruín Nazabal, Ana; Fernández Arévalo, María Mercedes; Álvarez Fuentes, Josefa; Holgado Villafuerte, María Ángeles;
Open Access English
  • Published: 01 Jan 2005
  • Country: Spain
Introduction Recent studies prove that the number of patients with inflammatory bowel disease is increasing all over the world due to contamination, industrialization and changes in the style of live. Some studies have shown that 5-aminosalicylic acid (5-ASA), an anti-inflammatory agent, must be the election treatment for these pathologies. In recent years, the production of microparticles systems seems to be equally promising to develop dosage forms in order to reduce the dosage frequency (1). On the other hand, the efficacy of this drug in the treatment of inflammatory bowel diseases may be optimized with a controlled release drug delivery system which maximiz...
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