Quercetin inhibits collagen-stimulated platelet activation through inhibition of multiple components of the glycoprotein VI signaling pathway

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Hubbard, G P ; Stevens, J M ; Cicmil, M ; Sage, T ; Jordan, P A ; Williams, C M ; Lovegrove, J A ; Gibbins, J M (2003)
  • Related identifiers: doi: 10.1046/j.1538-7836.2003.00212.x
  • Subject: Antioxidants | Calcium | Collagen | Dose-Response Relationship, Drug | Humans | Phosphorylation | Platelet Activation | Platelet Aggregation | Platelet Membrane Glycoproteins | Protein-Tyrosine Kinases | Quercetin | Signal Transduction | Tyrosine

The regulation of platelet function by pharmacological agents that modulate platelet signaling has proven a successful approach to the prevention of thrombosis. A variety of molecules present in the diet have been shown to inhibit platelet activation, including the anti... View more
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