Altered DNA methylation associated with a translocation linked to major mental illness

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Daniel L. McCartney; Rosie M. Walker; Stewart W. Morris; Susan M. Anderson; Barbara J. Duff; Riccardo E. Marioni; J. Kirsty Millar; Shane E. McCarthy; Niamh M. Ryan; Stephen M. Lawrie; Andrew R. Watson; Douglas H. R. Blackwood; Pippa A. Thomson; Andrew M. McIntosh; W. Richard McCombie; David J. Porteous; Kathryn L. Evans;
  • Publisher: Nature Publishing Group
  • Journal: npj Schizophrenia,volume 4 (issn: 2334-265X, eissn: 2334-265X)
  • Related identifiers: pmc: PMC5859082, doi: 10.1038/s41537-018-0047-7
  • Subject: Journal Article | Psychiatry | Article | RC435-571

<p>Recent work has highlighted a possible role for altered epigenetic modifications, including differential DNA methylation, in susceptibility to psychiatric illness. Here, we investigate blood-based DNA methylation in a large family where a balanced translocation betwe... View more
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