Altered DNA methylation associated with a translocation linked to major mental illness

Article English OPEN
McCartney, Daniel L.; Walker, Rosie M.; Morris, Stewart W.; Anderson, Susan M.; Duff, Barbara J.; Marioni, Riccardo E.; Millar, J. Kirsty; McCarthy, Shane E.; Ryan, Niamh M.; Lawrie, Stephen M.; Watson, Andrew R.; Blackwood, Douglas H. R.; Thomson, Pippa A.; McIntosh, Andrew M.; McCombie, W. Richard; Porteous, David J.; Evans, Kathryn L.;

<p>Recent work has highlighted a possible role for altered epigenetic modifications, including differential DNA methylation, in susceptibility to psychiatric illness. Here, we investigate blood-based DNA methylation in a large family where a balanced translocation betwe... View more