publication . Article . 2014

Bisfosfonatos: Aplicaciones Actuales en Osteoporosis y Cáncer

Augusto Poma Carmona; Guiselle Gutiérrez; Jorge Casas;
Open Access Spanish; Castilian
  • Published: 07 Apr 2014
  • Publisher: Facultad de Medicina Humana de la Universidad Nacional Mayor de San Marcos
Abstract
Bisphosphonates are antiresorptive agents with high affinity for hidroxiapatite crystals. They are not degraded by pyrophosphatases. Their main indications are treatment of post-menopausic osteoporosis, corticosteroid-induced osteoporosis, Paget´s disease, neoplasm-induced hypercalcemia and osteolytic bone disease by cancer. Los bisfosfonatos son compuestos antirresortivos con alta afinidad por los cristales de hidroxiapatita y no son degradados por las pirofosfatasas. Sus principales indicaciones son el tratamiento de la osteoporosis posmenopáusica, la inducida por corticoides, enfermedad de Paget, hipercalcemia asociada a neoplasias y la enfermedad osteolítica...
Subjects
Medical Subject Headings: musculoskeletal diseaseshormones, hormone substitutes, and hormone antagonists
free text keywords: Diphosphonates, Osteoporosis, Postmenopausal, Therapy, Bone Neoplasms, Osteitis Deformans, Difosfonatos, Osteoporosis Postmenopáusica, Terapia, Neoplasmas Óseos, Osteítis Deformante, Bone disease, medicine.disease, medicine, Disease, Surgery, medicine.medical_specialty, business.industry, business, Pyrophosphatases, Antiresorptive Agents, Cancer, Diabetes mellitus
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