publication . Article . Other literature type . 2015

Venomics and antivenomics of Bothrops erythromelas from five geographic populations within the Caatinga ecoregion of northeastern Brazil

Davinia Pla; Juan Calvete; Libia Sanz; Diva Nojosa; Rafael Ximenes; José María Gutiérrez; Diva Maria Borges Nojosa;
Open Access English
  • Published: 30 Jan 2015
  • Country: Costa Rica
The Caatinga lancehead, Bothrops erythromelas, is a medically relevant species, responsible for most of the snakebite accidents in most parts of its distribution range in northeastern Brazil. The spectrum and geographic variability of its venom toxins were investigated applying a venomics approach to venom pools from five geographic areas within the Caatinga ecoregion. Despite its wide habitat, populations of B. erythromelas from Ceará, Pernambuco, Juazeiro, Paraiba, and Ilha de Itaparica exhibit highly conserved venom proteomes. Mirroring their compositional conservation, the five geographic venom pools also showed qualitatively and quantitatively overlapping a...
free text keywords: Snake venom proteomics, Antivenomics, Bothrops neuwiedi complex, Bothrops erythromelas, Caatinga lancehead, Biophysics, Biochemistry
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