publication . Doctoral thesis . 2013

Avaliacao de polimorfismos nos genes XPD e XRCC3 em carcinomas orais de celulas escamosas

Pereira, Joabe dos Santos;
Open Access Portuguese
  • Published: 16 Sep 2013
  • Publisher: Universidade Federal do Rio Grande do Norte
Abstract
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Oral squamous cell carcinoma (OSCC) is an important cause of morbidity and mortality worldwide despite recent advances in treatment. There are several studies aiming to find markers that may improve the assessment of this disease prognosis. Studies about genetic polymorphisms have gained prominence due to their influence on individual susceptibility to cancer development. The aim of this study was to evaluate the association between the frequency of polymorphisms XPD Lys751Gln and XRCC3 Thr241Met and clinicopathological features of OSCC cases, including age, sex, presence or absence of metastases, and h...
Subjects
free text keywords: Carcinomas orais de células escamosas. Genes XPD. XRCC3, Carcinoma de células escamosas. Polimorfismos genéticos. Reparo de DNA. XPD. XRCC3. Polimorfismos de comprimento de fragmentos de restrição, :CIENCIAS DA SAUDE::ODONTOLOGIA [CNPQ]
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