publication . Article . 2009

Efectos clínicos a largo plazo en niños intoxicados con plomo en una región del sur de Chile

Carolina Coria; Aurora Cabello; Enzo Tassara; Eduardo López; Hugo Rosales; Marcelo Pérez; Claudia Zavala; Patricio Muñoz; Gabriel Orellana; María Isabel lnostroza; ...
Open Access Spanish
  • Published: 01 Aug 2009
  • Publisher: Sociedad Médica de Santiago
Abstract
Background: In 1996 there was a massive lead poisoning in a southern rural community in Chile. The contamination source was a mill whose grinding stone was repaired with lead and contaminated the flour. Aim: To assess the presence of sequelae ten years later, among subjects that were exposed to lead on that occasion. Material and methods: Cross sectional study of 77 individuals (47 males), aged 10 to 25 years, that were exposed to lead in 1996 and were treated with EDTA. Results: Twenty one percent of subjects had a subnormal intellingence quotient (IQ). The risk of having a low IQ was significantly higher among those exposed before the age of six years. IQ was ...
Subjects
free text keywords: Intelligence, Lead poisoning, nervous system, Neurotoxicity syndromes, General Medicine, Internal medicine, medicine.medical_specialty, medicine, business.industry, business, Gynecology, Accident prevention, Endocrinology
37 references, page 1 of 3

1. LANPHEAR B. Childhood lead poisoning prevention. JAMA 2005; 293: 2274-6. [OpenAIRE]

2. DEITRICH K. Enviromental neurotoxicants and psychological development. En: K.O Yeats, M.D. Ris and H.G. Taylor, Editors. Pediatric neuropsychology: research, theory and practice. Guilford Press, London (2000), 206-34.

3. CORY-SCHLECTA DA, SCHAUMBURG HH. Lead, inorganic. En: Spencer PS, Schaumburg HH, Ludolph AC, editors. Experimental and clinical neurotoxicology. 2nd ed. New York: Oxford University Press, 2000; 708-20.

4. CHEN A, CAI B, DIETRICH K, RADCLIFFE J, ROGAN W. Lead exposure, IQ, and behaviour in urban 5-7 year olds: Does lead affect behaviour only by lowering IQ? Pediatrics 2007; 119: e650-e658.

5. TCHERNITCHIN A, LAPIN N, MOLINA L, MOLINA G, TCHERNITCHIN N, ACEVEDO C, ALONSO P. Human Exposure to lead in Chile. Rev Environ Contam Toxicol 2006; 185: 93-139.

6. CANFIELD R, HENDERSON CR, CORY-SLECHTA D, COX C, JUSKO TA, LANPHEAR B. Intellectual impairment in children with blood lead concentrations below 10 micrograms per deciliter. N Engl J Med 2003; 348: 1517-26.

7. ROGAN W, WARE J. Exposure to lead in children: How low is low enough? N Engl J Med 2003; 348: 1515-6. [OpenAIRE]

8. ALONSO P, CASTRO H, DAVIS ME, GOZA J, HARGOUS J, RIVERA L, TASSARA E. Intoxicación por plomo: estudio epidemiológico Ñuble, Chile. EPI Visión, Ministerio de Salud, Chile, 1997; 10-5.

9. FERNÁNDEZ FJ. Micromethod for lead determination in whole blood by atomic absorption with use of the graphite furnace. Clin Chem 1975; 21: 558-61.

10. WECHSLER D. Test de inteligencia para niños WISC III. Manual. Psicometría y diagnóstico. Ed. Paidos, abril 1999.

11. WECHSLER D. Test de inteligencia para adultos WAIS. Manual. Psicometría y pasicodiagnóstico. Ed. Paidos, febrero 1992.

12. MINEDUC. Compendio de información estadística educacional 1999-2000. www.cep.cl/Cenda/Proyectos/Colegio_Profesores/Referencias/UNICEF/ Cobertura.pdf fecha de consulta 10 noviembre 2008.

13. BELLINGER D. Lead. Pediatrics 2004; 113: 1016-22.

14. BRADMAN A, ESKENAZI B, SUTTON P, ATHANASOULIS M, GOLDMAN LR. Iron deficiency associated with higher blood lead in children living in contaminated environments. Environ Health Perspect 2001; 109: 1079- 84.

15. KOLLER K, BROWN T, SPURGEON A, LEVY L. Recent developments in low-level lead exposure and intellectual impairment in children. Environ Health Perspect 2004; 112: 987-94.

37 references, page 1 of 3
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publication . Article . 2009

Efectos clínicos a largo plazo en niños intoxicados con plomo en una región del sur de Chile

Carolina Coria; Aurora Cabello; Enzo Tassara; Eduardo López; Hugo Rosales; Marcelo Pérez; Claudia Zavala; Patricio Muñoz; Gabriel Orellana; María Isabel lnostroza; ...