publication . Master thesis . 2016

AVALIAÇÃO DA ATIVIDADE DE TRÊS COMPOSTOS DO ÓLEO DE MELALEUCA SOBRE O Trypanosoma evansi

Baldissera, Matheus Dellaméa;
Open Access Portuguese
  • Published: 15 Feb 2016
  • Publisher: Universidade Federal de Santa Maria
Abstract
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior This study aimed the evaluation of the trypanocidal activity of terpinen-4-ol, γ-terpinene and α-terpinene against Trypanosoma evansi in vivo and in vitro. The in vitro assay was performed in culture medium of T. evansi, using three different concentrations of each compound (0.5, 1.0 and 2.0%), individually and in synergism. Motile (live) trypomastigotes were counted using a Neubauer chamber after 1, 3, 6 and 9 hours of incubation. Death of parasites occurred in a concentration-dependent manner, except for α-terpinene that was able to eliminate all parasites after 1 hour of incubation at all concentrati...
Subjects
free text keywords: Melaleuca alternifolia, Surra, Plantas medicinais, Tripanossomose, Medicinal plants, Tripanosomiasis, :CIENCIAS BIOLOGICAS::FARMACOLOGIA [CNPQ]
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