publication . Master thesis . 2012

Aceturato de diminazeno associado ao selenito de sódio e a vitamina E: testes in vitro e em ratos experimentalmente infectados com Trypanosoma evansi

Tonin, Alexandre Alberto;
Open Access Portuguese
  • Published: 27 Jan 2012
  • Publisher: Universidade Federal de Santa Maria
Abstract
Conselho Nacional de Desenvolvimento Científico e Tecnológico The aim of this study was to evaluate the utilization of a standard treatment with diminazene aceturate against the infection caused by T. evansi, associated to sodium selenite and vitamin E. In vitro tests showed trypanocidal effect related to the treatment with diminazene aceturate and sodium selenite, but vitamin E had no harmful effect on the trypanosomes. In vivo experiments utilized a total of 72 adult outbreed females rats, separated into 9 groups (A, B, C, D, E, F, G, H and I), 8 animals each. Group A was the uninfected group; groups B to I were infected with 0.2 mL of blood containing 106 try...
Subjects
free text keywords: Trypanosoma evansi, Aceturato de diminazeno, Selenito de sódio, Vitamina E, Roedores, Diminazene aceturate, Sodium selenite, Vitamin E, Rodents, :CIENCIAS BIOLOGICAS::FARMACOLOGIA [CNPQ]
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