Skeletal muscle necrosis induced by a phospholipase A2 isolated from the venom of the coral snake Micrurus nigrocinctus nigrocinctus.
Arroyo Gutiérrez, Olga; Rosso Julien, Jean Pierre; Vargas Rosso, Orietta; Gutiérrez, José María; Cerdas Fallas, Luis;
- Subject: Animals | Elapid venom | Mice | Microscopy | Muscles | Drug Effects | Necrosis | Phospholipases A2 | Snake venom
1. The venom of the coral snake Micrurus nigrocinctus nigrocinctus was fractionated by reverse-phase high performance liquid chromatography and an acidic myotoxic phospholipase A2 was purified to homogeneity. 2. After intramuscular injection, the toxin induced rapid and... View more
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