Antibody-mediated neutralization and binding-reversal studies on α-neurotoxins from micrurus nigrocinctus nigrocinctus (coral snake) venom

Article English OPEN
Alape Girón, Alberto; Stiles, Bradley G.; Gutiérrez, José María;
(1996)
  • Related identifiers: doi: 10.1016/0041-0101(95)00126-3
  • Subject: Immune Sera | Antivenins | Receptors, Cholinergic | Snake venom | Neurotoxins | Neutralization Tests | Elapidae | Guinea Pigs | Mice | Binding, Competitive | Immunization | Enzyme-Linked Immunosorbent Assay | Antibodies | Animals | Dose-Response Relationship, Drug | Elapid Venoms | Cross Reactions | Horses
    mesheuropmc: complex mixtures | nervous system

An ELISA based, non-radioactive acetylcholine receptor (AchR) binding assay was used to detect the alpha-neurotoxins present in Micrurus nigrocinctus nigrocinctus venom. Sera from horses hyperimmunized against M. nigrocinctus venom contain antibodies which inhibit the b... View more
Share - Bookmark