publication . Article . 2016

Trace elements levels in centenarian 'dodgers'.

Rafael Alis; Alejandro Santos-Lozano; Fabian Sanchis-Gomar; Helios Pareja-Galeano; Carmen Fiuza-Luces; Nuria Garatachea; Alejandro Lucia; Enzo Emanuele;
Open Access English
  • Published: 01 Jan 2016
  • Country: Switzerland
Abstract
Trace element bioavailability can play a role in several metabolic and physiological pathways known to be altered during the aging process. We aimed to explore the association of trace elements with increased lifespan by analyzing the circulating levels of seven trace elements (Cr, Cu, Fe, Mn, Mo, Se and Zn) in a cohort of healthy centenarians or ‘dodgers’ (≥100 years, free of major age-related diseases) in comparison with sex-matched younger elderly controls. Centenarians showed significant lower Cu (783.7 (76.7, 1608.9) vs 962.5 (676.3, 2064.4) μg/mL, P < 0.001), but higher Fe (1.3 (0.4, 4.7) vs 1.1 (0.5, 8.4) μg/mL, P = 0.003) and Se (85.7 (43.0, 256.7) vs 77...
Subjects
free text keywords: Geriatría, Anciano, Gerontología, Biochemistry, Selenium, chemistry.chemical_element, chemistry, Diabetes mellitus, medicine.disease, medicine, Gerontology, Trace element, Endocrinology, medicine.medical_specialty, Internal medicine, Centenarian, Cohort, Bioavailability
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publication . Article . 2016

Trace elements levels in centenarian 'dodgers'.

Rafael Alis; Alejandro Santos-Lozano; Fabian Sanchis-Gomar; Helios Pareja-Galeano; Carmen Fiuza-Luces; Nuria Garatachea; Alejandro Lucia; Enzo Emanuele;