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Цитоморфологическая диагностика и иммуноцитохимические исследования при раке молочной железы

Цитоморфологическая диагностика и иммуноцитохимические исследования при раке молочной железы

Abstract

Цитоморфологическое исследование – один из ведущих методов диагностики новообразований молочной железы (МЖ) на дооперационном поликлиническом этапе. Наличие образования в МЖ требует обязательного морфологического подтверждения. Точность (достоверность) тонкоигольной пункционной биопсии МЖ составляет 98,64%. В качестве альтернативы ИГХ методу все большее практическое значение в определении рецепторов эстрогенов, прогестерона и онкопротеина HER2/neu в клетках РМЖ приобретает метод определения экспрессии молекулярных маркеров на клеточном уровне – иммуноцитохимический (ИЦХ).

Сytomorphological study is one of the leading methods of diagnosis of tumors of the breast in the preoperative outpatient phase. The presence of a tumor in breast requires mandatory morphological confirmation. The accuracy (confidence) fine needle biopsy is 98,64%. Аs an alternative to IHC, immunocytochemistry (ICC) is of increasing practical importance in determination of estrogen receptor, progesterone, oncoprotein HER2/neu in breast cancer cells.

Keywords

рак молочной железы, иммуноцитохимия, рецепторы эстрогенов, рецепторы прогестерона, онкопротеин HER2/ neu, пролиферативная активность Ki67

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold
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