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Неврологические проявления микропролактином гипофиза у женщин детородного возраста

Неврологические проявления микропролактином гипофиза у женщин детородного возраста

Abstract

Микропролактинома является наиболее частой функционирующей аденомой гипофиза. В цепи патогенетических событий, развивающихся при функционировании микропролактиномы, ключевым звеном является синдром гиперпролактинемии, который запускает каскад нейроэндокринных изменений. Нами проанализировано 52 случая микропролактином гипофиза у пациенток репродуктивного возраста. Проведен анализ клинической картины неврологических проявлений у данной группы больных в зависимости от степени дефекта гормонального статуса. Показано, что описанный комплекс расстройств часто является облигатным и может преподноситься больными изолированно, без указания на сопутствующую гинекологическую симптоматику, что требует активного опроса на предмет нарушения овариально-менструального цикла.

Microprolactinoma is the most common functioning pituitary adenoma. In the chain of pathogenic events, developed du-ring microprolactinoma functioning, hyperprolactinemia syndrome is a key element, it starts a cascade of neuroendocrine changes. We have analyzed 52 cases of pituitary microprolactinoma in female patients of reproductive age. Clinical performance of neurological manifestations in this group of patients, depending on the extent of the defect in hormonal state, has been also analyzed. It is shown, that the described complex of disorders is often obligate, and it can be presented by patients singularly, without references to concomitant gynecological symptoms, that requires an active interview for violations of ovarian-menstrual cycle.

Keywords

МИКРОПРОЛАКТИНОМА ГИПОФИЗА,PITUITARY MIСROPROLACTINOMA,ПРОЛАКТИН,PROLACTIN,ГОРМОНАЛЬНЫЙ СТАТУС,HORMONAL STATUS,НЕВРОЛОГИЧЕСКИЕ ПРОЯВЛЕНИЯ,NEUROLOGIC MANIFESTATIONS,МіКРОПРОЛАКТИНОМА ГіПОФіЗА,ГОРМОНАЛЬНИЙ СТАТУС,НЕВРОЛОГіЧНі ПРОЯВИ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
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