Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Medical Perspectivesarrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
addClaim

This Research product is the result of merged Research products in OpenAIRE.

You have already added 0 works in your ORCID record related to the merged Research product.

Зменшення вираженості системного запалення як одна з основних цілей медикаментозного лікування пацієнтів з мультифокальним атеросклерозом в переді післяопераційний періоди реконструктивних оперативних втручань на судинах нижніх кінцівок

Зменшення вираженості системного запалення як одна з основних цілей медикаментозного лікування пацієнтів з мультифокальним атеросклерозом в переді післяопераційний періоди реконструктивних оперативних втручань на судинах нижніх кінцівок

Abstract

The aim of our study was to evaluate the expression of systemic inflammation in patients with multifocal atherosclerosis in preoperative period of reconstructive operative interventions on vessels of lower extremities and to estimate the clinical and anti-inflammatory efficiency of complex medicamental treatment in postoperative period in such category of patients. Significant increasing of blood plasma levels of C-reactive protein were revealed in patients with multifocal atherosclerosis.These results testified to the expressed systemic inflammatory reaction in patients with multifocal atherosclerosis. Complex medicamental treatment strategy in preand postoperative periods of reconstructive operative interventions on vessels of lower extremities provides the improving of life quality, increasing of distance of painless walking, increasing of ankle-brachial index, decreasing of intima-media complex, diminishing of total cholesterol, low density lipoproteins, triglycerides, C-reactive protein levels. Besides, complex therapy was well tolerated by patients – serious adverse effects of treatment were not registered.

В исследовании изучалась выраженность системного воспаления у больных с мультифокальным атеросклерозом в предоперационном периоде реконструктивных оперативных вмешательств на сосудах нижних конечностей и оценивалась клиническая и противовоспалительная эффективность комплексного медикаментозного лечения в послеоперационном периоде у этой категории пациентов. У пациентов с мультифокальным атеросклерозом выявлено достоверное (по сравнению с лицами контрольной группы) увеличение в плазме крови уровня С-реактивного белка, что свидетельствует о наличии системного хронического воспаления. Комплексный подход к медикаментозному лечению пациентов с мультифокальным атеросклерозом в преди послеоперационный периоды реконструктивных оперативных вмешательств на сосудах нижних конечностей способствует улучшению качества жизни больных, увеличению дистанции «безболевой» ходьбы, приводит к достоверному увеличению лодыжечно-плечевого индекса, уменьшению толщины комплекса «интима-медиа», достоверному уменьшению уровней ОХ крови, холестерина ЛПНП, триглицеридов, индекса атерогенности, С-реактивного белка.

Keywords

ХРОНіЧНА іШЕМіЧНА ХВОРОБА СЕРЦЯ, АТЕРОСКЛЕРОТИЧНЕ УРАЖЕННЯ АРТЕРіЙ НИЖНіХ КіНЦіВОК, С-РЕАКТИВНИЙ БіЛОК, МЕДИКАМЕНТОЗНЕ ЛіКУВАННЯ, ОПЕРАТИВНЕ ЛіКУВАННЯ, СТАТИНИ

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold
Related to Research communities