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Фенотипы дислипидемии у женщин репродуктивного возраста с функциональной гиперандрогенией и нормальной или избыточной массой тела

Фенотипы дислипидемии у женщин репродуктивного возраста с функциональной гиперандрогенией и нормальной или избыточной массой тела

Abstract

The purpose of investigation was to revel the features of dislipidemia in women of reproductive age with functional hyperandrogyny (FHA) and excessive body mass. 61 women with FHA with normal and excessive body mass and 30 healthy women aged 21-45 years have been examined. There have been defined the lipids and subfractions of lipoproteins on an empty stomach and during oral test on tolerance to glucose. The indices of aterodenicity (Klimova A.N. and Thompson G.R., 1991, 1997 y) have been estimated and sensitivity to insulin has been defined (Stumvoll M., 2000). It has been established that excessive weight and FHA promote aterogenic changes in lipidogram in women of reproductive age and these changes are more expressed in combination of both factors.

Целью исследования было выявить особенности дислипидемии у женщин репродуктивного возраста с функциональной гиперандрогенией (ФГА) и избыточной массой тела. Обследованы 61 женщина с ФГА с нормальным или избыточным весом и 30 здоровых женщин в возрасте от 21 года до 45 лет. Определялись липиды и субфракции липопротеидов натощак и в ходе орального теста на толерантность к глюкозе. Оценивались индексы атерогенности (А.Н. Климов и G.R. Thompson, 1991, 1997) и определялась чувствительность к инсулину (М. Stumvoll, 2000). Установлено, что избыточный вес и ФГА способствуют появлению атерогенных сдвигов в липидограмме у женщин репродуктивного возраста, большей степени выраженных при сочетании обоих факторов.

Keywords

ДИСЛИПИДЕМИЯ, ЖЕНЩИНЫ, РЕПРОДУКТИВНЫЙ ВОЗРАСТ, ФУНКЦИОНАЛЬНАЯ ГИПЕРАНДРОГЕНЕМИЯ, ИЗБЫТОЧНАЯ МАССА ТЕЛА

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average