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Практическое значение и желчеустойчивость коллекционных штаммов Lactobacillus acidophilus

Практическое значение и желчеустойчивость коллекционных штаммов Lactobacillus acidophilus

Abstract

The intestine microecology is characterized by the presence of bile produced in the liver cells. Besides its main functions associated with digestion, bile (more exactly, bile acids contains in it) prevents adhesion of the exogenous microbes to the intestinal epithelium. Strains Lactobacillus acidophilus are quite resistant to gall and have adapted to this ecological niche. For example, in contrast to the strains of the Bulgarian sticks, unable to colonize the intestine, they sustain the presence of bile salts in concentration 20% in the nutrient medium. The article presents comparative data on bile tolerance of the collection strains Lactobacillus acidophilus (from the collection of Microbiology laboratory of Siberian cheesemaking research Institute, Barnaul) which are promising for inclusion to the probiotic dairy products. The most resistant to high concentrations of bile and the weakest strains Lactobacillus acidophilus have been identified. Also the basic promising and widely used practical importance of Lactobacillus acidophilus are discussed in the article. Possible advantages and disadvantages of using acidophilic bacteria in various sectors, the quality of acidophilic products and drugs are shown.

Микроэкология кишечника характеризуется присутствием желчи, продуцируемой клетками печени. Помимо своих основных функций, связанных с пищеварением, желчь (точнее, содержащиеся в ней желчные кислоты) предупреждает адгезию экзогенных микробов к кишечному эпителию. Штаммы L. acidophilus, приспособившиеся к данной экологической нише, проявляют довольно высокую устойчивость к желчи; например, в отличие от штаммов болгарской палочки, неспособной колонизировать кишечник, они выдерживают присутствие в питательной среде солей желчи в концентрации 20%. В статье представлены сравнительные данные по желчеустойчивости коллекционных штаммов L. acidophilus (из коллекции лаборатории микробиологии Сибирского НИИ сыроделия, Барнаул), перспективных для включения в состав пробиотических молочных продуктов. Выявлены самые устойчивые к высоким концентрациям желчи и самые слабые штаммы L. acidophilus. Также рассмотрены основные перспективные и широко распространенные направления практического применения L. acidophilus; приведены возможные преимущества и недостатки использования ацидофильных бактерий в различных отраслях, отражены проблемы качества ацидофильных продуктов и препаратов.

Keywords

МОЛОЧНОКИСЛЫЕ БАКТЕРИИ, АЦИДОФИЛЬНАЯ ПАЛОЧКА, ЖЕЛЧЬ, ПРАКТИЧЕСКОЕ ЗНАЧЕНИЕ

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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold