The content, relevant problems and experience of forming the large-scale informational and analytic system (IAS) designed and created in the Institute of economy of industry of NAS of Ukraine are developed. IAS is assigned for the economic and mathematical modelling of financial and economic development of a region, construction of medium-term scenarios of development and assessment of consequences of economic decisions accepted by the central authorities and economic subjects (population of the region, small and large enterprises and organizations). IAS comprises mathematical models of the region’s economy; statistical and other relevant information database essential for the designing and verification of these models; software that provides users with the possibility of practical application of IAS; organisation of the management of a single complex of IAS. In the article the methodology is exposed and the choice of economic and mathematical modelling tools is grounded, the short mathematical description of the complex of models, which constitute IAS, is provided. In turn, these mo

Раскрыто содержание, рассмотрены проблемы и приведен опыт формирования крупномасштабной информационно-аналитической системы, предназначенной для экономико-математического моделирования финансово-экономического развития области, построения среднесрочных сценариев развития и оценки последствий хозяйственных решений, принимаемых органами власти и экономическими субъектами.