publication . Other literature type . Article . 2005

Bats Are Natural Reservoirs of SARS-Like Coronaviruses

Wendong Li; Zhengli Shi; Meng Yu; Wuze Ren; Craig Smith; Jonathan H. Epstein; Hanzhong Wang; Gary Crameri; Zhihong Hu; Huajun Zhang; ...
Open Access
  • Published: 31 Oct 2005
  • Publisher: American Association for the Advancement of Science (AAAS)
Abstract
Severe acute respiratory syndrome (SARS) emerged in 2002 to 2003 in southern China. The origin of its etiological agent, the SARS coronavirus (SARS-CoV), remains elusive. Here we report that species of bats are a natural host of coronaviruses closely related to those responsible for the SARS outbreak. These viruses, termed SARS-like coronaviruses (SL-CoVs), display greater genetic variation than SARS-CoV isolated from humans or from civets. The human and civet isolates of SARS-CoV nestle phylogenetically within the spectrum of SL-CoVs, indicating that the virus responsible for the SARS outbreak was a member of this coronavirus group. Several species of bat livin...
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Medical Subject Headings: virusesskin and connective tissue diseasesfungibody regionsvirus diseases
free text keywords: Multidisciplinary, Viridae, corona viruses, biotic associations, CETAF-taskforce, covid, covid-19, pathogens, biotic interaction, virus-host, biotic relations, pathogen-host, Outbreak, Biology, Civet, biology.organism_classification, Virus, Virology, Coronavirus, medicine.disease_cause, medicine, Nidovirales, Alphacoronavirus, Disease reservoir, Coronaviridae
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