publication . Other literature type . Preprint . 2019

Population management using gene drive: molecular design, spread dynamics modelling and assessment of ecological risks

Rode, Nicolas O.; Estoup, Arnaud; Bourguet, Denis; Courtier-Orgogozo, Virginie; Débarre, Florence;
Open Access English
  • Published: 16 Feb 2019
  • Publisher: Zenodo
Abstract
Gene drive has recently been proposed as a promising technology for population management, including in conservation genetics; it is based on the release of genetically engineered individuals designed to rapidly propagate a desired mutation or transgene to high frequencies in wild populations. Potential applications in conservation biology include the control of invasive pest populations that threaten biodiversity (eradication and suppression drives), or the introduction of beneficial mutations in endangered populations (rescue drives). We examine the challenges posed by the evolution of resistance to gene drives and review the various environmental risks associ...
Subjects
free text keywords: invasive species, endangered species, genetic population management, conservation genetics, assisted gene flow, genetic rescue
Download fromView all 5 versions
Zenodo
Other literature type . 2019
Provider: Datacite
Zenodo
Other literature type . 2018
Provider: Datacite
ZENODO
Preprint . 2019
Provider: ZENODO
ZENODO
Preprint . 2018
Provider: ZENODO
Powered by OpenAIRE Open Research Graph
Any information missing or wrong?Report an Issue
publication . Other literature type . Preprint . 2019

Population management using gene drive: molecular design, spread dynamics modelling and assessment of ecological risks

Rode, Nicolas O.; Estoup, Arnaud; Bourguet, Denis; Courtier-Orgogozo, Virginie; Débarre, Florence;