publication . Other literature type . Article . 2017

SOLUBILITY ENHANCEMENT OF NIFEDIPINE BY USING LIQUISOLID COMPACT TECHNIQUE

Derle Deeliprao*, Ingle Vaibhav, Patel Poonam*, Derle Nikita*;
Open Access
  • Published: 28 Feb 2017
  • Publisher: Zenodo
Abstract
This study evaluated the feasibility of liquisolid compact as an innovative drug delivery system to improve the solubility of the poorly soluble drug Nifedipine. There are several techniques to enhance the dissolution of poorly soluble drugs. Among them, the technique of liquisolid compact is most promising technique towards novel aim. Several formulations of liquisolid compact having different drug concentration (20-40% w/w) and with varying ratios of carrier and coating material (i.e. different R value, from15-20) were prepared. In this study Polyethylene glycol 400 (PEG400) as a solvent, Avicel PH 102 as a carrier and Aerosil-200 as a coating material were us...
Subjects
free text keywords: Nifedipine; Liquisolid Compact; PEG 400; Carrier Material; Coating Material; Poorly Water Soluble Drugs.
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Zenodo
Other literature type . 2017
Provider: Datacite
Zenodo
Other literature type . 2017
Provider: Datacite
ZENODO
Article . 2017
Provider: ZENODO
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