publication . Article . 2017

Effect of Curcumin on Blood Glucose Level and Some Neurobehavioral Responses in Alloxan-induced Diabetic Swiss Albino Mice

U Garkuwa; A Alhassan; Y Tanko;
Open Access
  • Published: 10 Jan 2017
Abstract
The aim of this study was to evaluate the effect of curcumin on blood glucose level and neurobehavioral response in Alloxan-induced diabetic Swiss Albino mice. The animals were divided into five (5) groups of four each (n=4). Group I served as control and received distilled water, group II, III, IV and V were diabetic and received olive oil 1 ml/kg, glibenclamide 1 mg/kg, curcumin 50 mg/kg and curcumin 100 mg/kg respectively. Diabetes was induced using Alloxan (150 mg/kg). All administrations were done for duration of 21 days. Blood glucose level was determined using glucose oxidase principle and cognitive impairment was determined using novel object recognition...
Subjects
free text keywords: Curcumin, cognitive impairment, mice, diabetes, chemistry.chemical_compound, chemistry, Alloxan, Pharmacology, Medicine, business.industry, business
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