publication . Article . 2017

Effect of Curcumin on Blood Glucose Level and Some Neurobehavioral Responses in Alloxan-induced Diabetic Swiss Albino Mice

U Garkuwa; A Alhassan; Y Tanko;
Open Access
  • Published: 10 Jan 2017
The aim of this study was to evaluate the effect of curcumin on blood glucose level and neurobehavioral response in Alloxan-induced diabetic Swiss Albino mice. The animals were divided into five (5) groups of four each (n=4). Group I served as control and received distilled water, group II, III, IV and V were diabetic and received olive oil 1 ml/kg, glibenclamide 1 mg/kg, curcumin 50 mg/kg and curcumin 100 mg/kg respectively. Diabetes was induced using Alloxan (150 mg/kg). All administrations were done for duration of 21 days. Blood glucose level was determined using glucose oxidase principle and cognitive impairment was determined using novel object recognition...
free text keywords: Curcumin, cognitive impairment, mice, diabetes, chemistry.chemical_compound, chemistry, Alloxan, Pharmacology, Medicine, business.industry, business
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