publication . Article . 2006

Effectiveness of seven-valent pneumococcal conjugate vaccine against invasive pneumococcal disease: a matched case-control study

Whitney, Cynthia G.; Pilishvili, Tamar; Farley, Monica M.; Schaffner, William; Craig, Allen S.; Lynfield, Ruth; Nyquist, Ann-Christine; Gershman, Kenneth A.; Vazquez, Marietta; Bennett, Nancy M.; ...
  • Published: 01 Oct 2006
  • Publisher: Elsevier BV
Abstract
Summary Background In March 2010, Brazil introduced the ten-valent pneumococcal conjugate vaccine (PCV10), which was licensed based on non-inferiority of immunological correlates of protection compared with the seven-valent vaccine. The schedule comprised three primary doses at ages 2 months, 4 months, and 6 months, and a booster dose at age 12 months. A single catch-up dose was offered for children aged 12–23 months at the time of introduction. We assessed PCV10 effectiveness against invasive pneumococcal disease in Brazilian children. Methods Invasive pneumococcal disease, defined as isolation of Streptococcus pneumoniae from blood, cerebrospinal fluid, or ano...
Subjects
free text keywords: Case-control study, Disease, Serotype, Surgery, medicine.medical_specialty, medicine, business.industry, business, Pneumococcal 7-Valent Conjugate Vaccine, Streptococcus pneumoniae, medicine.disease_cause, Booster dose, Odds ratio, Internal medicine, Pneumococcal conjugate vaccine, medicine.drug, Immunology
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publication . Article . 2006

Effectiveness of seven-valent pneumococcal conjugate vaccine against invasive pneumococcal disease: a matched case-control study

Whitney, Cynthia G.; Pilishvili, Tamar; Farley, Monica M.; Schaffner, William; Craig, Allen S.; Lynfield, Ruth; Nyquist, Ann-Christine; Gershman, Kenneth A.; Vazquez, Marietta; Bennett, Nancy M.; ...