publication . Article . 2021

SUMCASTEC_210112_High Frequency Dielectrophorosis Cytometer for Continuous Flow Biological Cells Refinement

Thomas Provent; Audrey Mauvy; Rémi Manczak; Sofiane Saada; Claire Dalmay; Barbara Bessette; Fabrice Lalloué; Arnaud Pothier;
Open Access English
  • Published: 12 Jan 2021
This paper presents a microfluidic radiofrequency device operating at a few hundred MHz, which is able to sort biological cells. It uses a non-invasive and label-free technic based on intracellular dielectric specificities of biological cells. The sorting principle relies on a dynamic dielectrophoresis (DEP) deviation resulting from the interaction between a high frequency electric signal and the cell cytoplasm content. Driven in a microfluidic channel by a continuous flow, cells are individually deflected from their primary trajectories after having entered a non-uniform electric field generated by a microelectrode system. Designed with different slopes, these ...
Funded by
Semiconductor-based Ultrawideband Micromanipulation of CAncer STEm Cells
  • Funder: European Commission (EC)
  • Project Code: 737164
  • Funding stream: H2020 | RIA
FET H2020FET OPEN: FET-Open research and innovation actions
FET H2020FET OPEN: Semiconductor-based Ultrawideband Micromanipulation of CAncer STEm Cells
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Article . 2021
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