publication . Article . 2013

Quantitative Liver Lesion Volume Determination by Nanoparticle-Based SPECT

Dániel S. Veres; Domokos Máthé; Ildikó Futó; Ildikó Horváth; Ákos Balázs; Kinga Karlinger; Krisztián Szigeti;
Open Access
  • Published: 31 Aug 2013
Abstract
PURPOSE: The aim of this paper is to present a simple and quantitative data analysis method with a new potential in the application of liver single-photon emission computed tomography (SPECT) imaging. We have established quantitative SPECT/computed tomography (CT) in vivo imaging protocols for determination of liver tumor burden based on the known role of Kupffer cells in cancer of the liver. PROCEDURES: As it is also known that functional Kupffer cells accumulate particulate material contained in the arterial blood of liver supply, we used radiolabeled macro-aggregated albumin particles ([(99m)Tc]-MAA) injected intravenously to image liver disease. Quantificati...
Subjects
free text keywords: hepatocellular carcinoma (HCC), SPECT/CT, quantification, particle, macro-aggregated albumin, Kupffer cell, Cancer Research, Oncology, Radiology Nuclear Medicine and imaging, Volume determination, Computed tomography, medicine.diagnostic_test, medicine, medicine.anatomical_structure, Liver tumor, medicine.disease, Nuclear medicine, business.industry, business, Emission computed tomography, Radiology, medicine.medical_specialty, Liver lesion, Preclinical imaging, Cancer
Funded by
EC| INMIND
Project
INMIND
Imaging of Neuroinflammation in Neurodegenerative Diseases
  • Funder: European Commission (EC)
  • Project Code: 278850
  • Funding stream: FP7 | SP1 | HEALTH
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publication . Article . 2013

Quantitative Liver Lesion Volume Determination by Nanoparticle-Based SPECT

Dániel S. Veres; Domokos Máthé; Ildikó Futó; Ildikó Horváth; Ákos Balázs; Kinga Karlinger; Krisztián Szigeti;