publication . Article . Other literature type . 1997

Implication of Right Frontostriatal Circuitry in Response Inhibition and Attention-Deficit/Hyperactivity Disorder

Daniel P. Dickstein; F. Xavier Castellanos; Judith L. Rapoport; B. J. Casey; Susan D. Hamburger; W.L. Marsh; Anne B. Schubert; A. Catherine Vaituzis; Stacey E. Sarfatti; Jay N. Giedd; ...
Open Access
  • Published: 01 Mar 1997
Abstract
ABSTRACT Objective To examine the relation between specific frontostriatal structures (prefrontal cortex and basal ganglia) and response inhibition deficits observed in attention-deficit/hyperactivity disorder (ADHD). Method Children with ADHD and age-matched normal controls were scanned using magnetic resonance imaging (MRI) and tested on three response inhibition tasks. Behavioral performance was correlated with MRI-based anatomical measures of frontostriatal circuitry (prefrontal cortex and basal ganglia) implicated in ADHD. Results First, significant differences in performance by children with ADHD and normal volunteers were observed on all three response in...
Subjects
Medical Subject Headings: behavioral disciplines and activities
free text keywords: Developmental and Educational Psychology, Psychiatry and Mental health, Central nervous system, medicine.anatomical_structure, medicine, Laterality, Prefrontal cortex, Basal ganglia, Impulsivity, medicine.symptom, Globus pallidus, Psychology, Attention deficit hyperactivity disorder, medicine.disease, Neuroscience, Putamen
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