publication . Article . 2018 . Embargo end date: 01 Jan 2018

Physiologically based pharmacokinetic (PBPK) modeling of the bisphenols BPA, BPS, BPF, and BPAF with new experimental metabolic parameters: Comparing the pharmacokinetic behavior of BPA with its substitutes

Cecile Karrer; Thomas Roiss; Natalie von Goetz; Darja Gramec Skledar; Lucija Peterlin Mašič; Konrad Hungerbühler;
Open Access English
  • Published: 01 Jul 2018
  • Publisher: ETH Zurich
  • Country: Switzerland
Abstract
ISSN:1552-9924
Subjects
Medical Subject Headings: hormones, hormone substitutes, and hormone antagonistsurologic and male genital diseasesendocrine system
free text keywords: Public Health, Environmental and Occupational Health, Health, Toxicology and Mutagenesis, PBPK modeling, BPA, Bisphenol analogs, Research, Pharmacology, Bisphenol A, chemistry.chemical_compound, chemistry, Pharmacokinetics, Physiologically based pharmacokinetic modelling
Related Organizations
Funded by
EC| EuroMix
Project
EuroMix
EuroMix
  • Funder: European Commission (EC)
  • Project Code: 633172
  • Funding stream: H2020 | RIA
Validated by funder
Communities
Agricultural and Food Sciences
SDSN - GreeceSustainable Development Projects: EuroMix
Rural Digital Europe
99 references, page 1 of 7

Barter ZE, Bayliss MK, Beaune PH, Boobis AR, Carlile DJ, Edwards RJ, et al.2007. Scaling factors for the extrapolation of in vivo metabolic drug clearance from in vitro data: reaching a consensus on values of human micro-somal protein and hepatocellularity per gram of liver. Curr Drug Metab 8(1):33–45, PMID: 17266522, 10.2174/138920007779315053.17266522 [OpenAIRE] [PubMed] [DOI]

Bautista-Toledo I, Ferro-García MA, Rivera-Utrilla J, Moreno-Castilla C, Vegas Fernández FJ 2005. Bisphenol A removal from water by activated carbon. effects of carbon characteristics and solution chemistry. Environ Sci Technol 39(16):6246–6250, PMID: 16173588, 10.1021/es0481169.16173588 [OpenAIRE] [PubMed] [DOI]

Biedermann S, Tschudin P, Grob K 2010. Transfer of bisphenol A from thermal printer paper to the skin. Anal Bioanal Chem 398(1):571–576, PMID: 20623271, 10.1007/s00216-010-3936-9.20623271 [OpenAIRE] [PubMed] [DOI]

Boucher JG, Boudreau A, Ahmed S, Atlas E 2015. In vitro effects of bisphenol A β-D-Glucuronide (BPA-G) on adipogenesis in human and murine preadipocytes. Environ Health Perspect 123(12):1287–1293, PMID: 26018136.26018136 [OpenAIRE] [PubMed]

Brown RP, Delp MD, Lindstedt SL, Rhomberg LR, Beliles RP 1997. Physiological parameter values for physiologically based pharmacokinetic models. Toxicol Ind Health 13(4):407–484, PMID: 9249929, 10.1177/074823379701300401.9249929 [OpenAIRE] [PubMed] [DOI]

Calafat AM, Ye X, Wong L-Y, Reidy JA, Needham LL 2008. Exposure of the U.S. population to bisphenol A and 4-tertiary-Octylphenol: 2003-2004 test. Environ Health Perspect 116(1):39–44, PMID: 18197297, 10.1289/ehp.10753.18197297 [OpenAIRE] [PubMed] [DOI]

Chen D, Kannan K, Tan H, Zheng Z, Feng Y-L, Wu Y, et al.2016. Bisphenol analogues other than BPA: environmental occurrence, human exposure, and toxicity—a review. Environ Sci Technol 50(11):5438–5453, PMID: 27143250, 10.1021/acs.est.5b05387.27143250 [OpenAIRE] [PubMed] [DOI]

Choi YJ, Lee LS 2017. Partitioning behavior of bisphenol alternatives BPS and BPAF compared to BPA. Environ Sci Technol 51(7):3725–3732, PMID: 28274112, 10.1021/acs.est.6b05902.28274112 [OpenAIRE] [PubMed] [DOI]

Coughlin JL, Thomas PE, Buckley B 2012. Inhibition of genistein glucuronidation by bisphenol A in human and rat liver microsomes. Drug Metab Dispos 40(3):481–485, PMID: 22146138, 10.1124/dmd.111.042366.22146138 [OpenAIRE] [PubMed] [DOI]

Covaci A, Hond ED, Geens T, Govarts E, Koppen G, Frederiksen H, et al.2015. Urinary BPA measurements in children and mothers from six European member states: overall results and determinants of exposure. Environ Res 141:77–85, PMID: 25440295, 10.1016/j.envres.2014.08.008.25440295 [OpenAIRE] [PubMed] [DOI]

DeJongh J, Verhaar HJM, Hermens JLM 1997. A quantitative property-property relationship (QPPR) approach to estimate in vitro tissue-blood partition coefficients of organic chemicals in rats and humans. Arch Toxicol 72(1):17–25, PMID: 9458186, 10.1007/s002040050463.9458186 [OpenAIRE] [PubMed] [DOI]

Demierre A-L, Peter R, Oberli A, Bourqui-Pittet M 2012. Dermal penetration of bisphenol A in human skin contributes marginally to total exposure. Toxicol Lett 213(3):305–308, PMID: 22796587, 10.1016/j.toxlet.2012.07.001.22796587 [OpenAIRE] [PubMed] [DOI]

Doerge DR, Twaddle NC, Vanlandingham M, Brown RP, Fisher JW 2011. Distribution of bisphenol A into tissues of adult, neonatal, and fetal Sprague–Dawley rats. Toxicol Appl Pharmacol 255(3):261–270, PMID: 21820460, 10.1016/j.taap.2011.07.009.21820460 [OpenAIRE] [PubMed] [DOI]

Draganov DI, Markham DA, Beyer D, Waechter JM, Dimond SS, Budinsky RA, et al.2015. Extensive metabolism and route-dependent pharmacokinetics of bisphenol A (BPA) in neonatal mice following oral or subcutaneous administration. Toxicology 333:168–178., PMID: 25929835, 10.1016/j.tox.2015.04.012.25929835 [OpenAIRE] [PubMed] [DOI]

Dumont C, Perdu E, Sousa G, de Debrauwer L, Rahmani R, Cravedi J-P, et al.2011. Bis(hydroxyphenyl)methane—bisphenol F—metabolism by the HepG2 human hepatoma cell line and cryopreserved human hepatocytes. Drug Chem Toxicol 34(4):445–453, PMID: 21770713, 10.3109/01480545.2011.585651.21770713 [OpenAIRE] [PubMed] [DOI]

99 references, page 1 of 7
Any information missing or wrong?Report an Issue